Basic equipment needs include a computer with design software and an output device to create film, screens, a coating trough, an exposure unit with a vacuum frame, a developing sink, a pressure washer, drying racks, a reclaim sink, ink, a scale, a color matching system, and a press.
If you have the initial capital, some extras you might want to think about include an automatic coating system, automatic Computer-to-Screen (CTS) output with onboard exposure, automatic developing with pre-registration fixturing for ease of setup, and an automatic reclaim system.
—GraphicElephants.com